Question to Dr. A, about the Retention Factor or Rf in ysing gesic tablets by TLC?

Both molecules seem similar in terms of polarity. (Both have polar acids and nonpolar benzine rings.) This makes it difficult ume which would move quicker down the column. (Or slide for this test.) You could run a computer model determining interactions between the molecules and the solvents, but even then the best test is a real test.